Mice with an N-ethyl-N-nitrosourea (ENU) induced Tyr209Asn mutation in natriuretic peptide receptor 3 (NPR3) provide a model for kyphosis associated with activation of the MAPK signaling pathway

Mice with an N-ethyl-N-nitrosourea (ENU) induced Tyr209Asn mutation in natriuretic peptide receptor 3 (NPR3) provide a model for kyphosis associated with activation of the MAPK signaling pathway

Non-syndromic kyphosis is a common disorder that is associated with significant morbidity and has a strong genetic involvement; however, the causative genes remain to be identified, as such studies are hampered by genetic heterogeneity, small families and various modes of inheritance. To overcome th...

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Príomhchruthaitheoirí:	Esapa, C, Piret, S, Nesbit, M, Loh, N, Thomas, G, Croucher, P, Brown, M, Brown, S, Cox, R, Thakker, R
Formáid:	Journal article
Teanga:	English
Foilsithe / Cruthaithe:	Public Library of Science 2016

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