Insulin-like growth factors 1 and 2 induce lymphangiogenesis in vivo.

Lymphangiogenesis is an important process that contributes to the spread of cancer. Here we show that insulin-like growth factors 1 (IGF-1) and 2 (IGF-2) induce lymphangiogenesis in vivo. In a mouse cornea assay, IGF-1 and IGF-2 induce lymphangiogenesis as detected with LYVE-1, a specific marker for...

Full description

Bibliographic Details
Main Authors: Björndahl, M, Cao, R, Nissen, L, Clasper, S, Johnson, L, Xue, Y, Zhou, Z, Jackson, D, Hansen, A, Cao, Y
Format: Journal article
Language:English
Published: 2005