Genome-scale methods converge on key mitochondrial genes for the survival of human cardiomyocytes in hypoxia.

BACKGROUND: Any reduction in myocardial oxygen delivery relative to its demands can impair cardiac contractile performance. Understanding the mitochondrial metabolic response to hypoxia is key to understanding ischemia tolerance in the myocardium. We used a novel combination of 2 genome-scale method...

詳細記述

書誌詳細
主要な著者: Edwards, L, Sigurdsson, M, Robbins, P, Weale, M, Cavalleri, G, Montgomery, H, Thiele, I
フォーマット: Journal article
言語:English
出版事項: 2014