A novel image-based high throughput screening assay discovers therapeutic candidates for adult polyglucosan body disease
Glycogen storage disorders (GSDs) are caused by excessive accumulation of glycogen. Some GSDs (Adult Polyglucosan Body Disease (APBD), Tarui and Lafora diseases) are caused by intracellular accumulation of insoluble inclusions, called polyglucosan bodies (PB), which are chiefly composed of malconstr...
Hlavní autoři: | Solmesky, L, Khazanov, N, Senderowitz, H, Wang, P, Minassian, B, Ferreira, I, Yue, W, Lossos, A, Weil, M, Kakhlon, O |
---|---|
Médium: | Journal article |
Jazyk: | English |
Vydáno: |
Portland Press
2017
|
Podobné jednotky
-
Guaiacol as a drug candidate for treating adult polyglucosan body disease
Autor: Kakhlon, O, a další
Vydáno: (2018) -
Alleviation of a polyglucosan storage disorder by enhancement of autophagic glycogen catabolism
Autor: Or Kakhlon, a další
Vydáno: (2021-09-01) -
Polyglucosan bodies in medullary catecholaminergic neurons in SUDEP
Autor: Smriti Patodia, a další
Vydáno: (2021-01-01) -
Amylopectinosis of the fatal epilepsy Lafora disease resists autophagic glycogen catabolism
Autor: Jun Wu, a další
Vydáno: (2024-04-01) -
GYG1: A distal myopathy with polyglucosan bodies
Autor: Stefan Nicolau, a další
Vydáno: (2020-09-01)