A novel image-based high throughput screening assay discovers therapeutic candidates for adult polyglucosan body disease
Glycogen storage disorders (GSDs) are caused by excessive accumulation of glycogen. Some GSDs (Adult Polyglucosan Body Disease (APBD), Tarui and Lafora diseases) are caused by intracellular accumulation of insoluble inclusions, called polyglucosan bodies (PB), which are chiefly composed of malconstr...
Үндсэн зохиолчид: | Solmesky, L, Khazanov, N, Senderowitz, H, Wang, P, Minassian, B, Ferreira, I, Yue, W, Lossos, A, Weil, M, Kakhlon, O |
---|---|
Формат: | Journal article |
Хэл сонгох: | English |
Хэвлэсэн: |
Portland Press
2017
|
Ижил төстэй зүйлс
Ижил төстэй зүйлс
-
Guaiacol as a drug candidate for treating adult polyglucosan body disease
-н: Kakhlon, O, зэрэг
Хэвлэсэн: (2018) -
Alleviation of a polyglucosan storage disorder by enhancement of autophagic glycogen catabolism
-н: Or Kakhlon, зэрэг
Хэвлэсэн: (2021-09-01) -
Polyglucosan bodies in medullary catecholaminergic neurons in SUDEP
-н: Smriti Patodia, зэрэг
Хэвлэсэн: (2021-01-01) -
Amylopectinosis of the fatal epilepsy Lafora disease resists autophagic glycogen catabolism
-н: Jun Wu, зэрэг
Хэвлэсэн: (2024-04-01) -
GYG1: A distal myopathy with polyglucosan bodies
-н: Stefan Nicolau, зэрэг
Хэвлэсэн: (2020-09-01)