Identification of thiotetronic acid antibiotic biosynthetic pathways by target-directed genome mining
Recent genome sequencing efforts have led to the rapid accumulation of uncharacterized or “orphaned” secondary metabolic biosynthesis gene clusters (BGCs) in public databases. This increase in DNA-sequenced big data has given rise to significant challenges in the applied field of natural product gen...
Main Authors: | Tang, X, Li, J, Millán-Aguiñaga, N, Zhang, J, O’Neill, E, Ugalde, J, Jensen, P, Mantovani, S, Moore, B |
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Format: | Journal article |
Published: |
American Chemical Society
2015
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