Recovery from hypoxia‐induced internalization of cardiac Na+/H + exchanger 1 requires an adequate intracellular store of antioxidants

The heart is highly active metabolically but relatively underperfused and, therefore, vulnerable to ischemia. In addition to acidosis, a key component of ischemia is hypoxia that can modulate gene expression and protein function as part of an adaptive or even maladaptive response. Here, using cardia...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Şimşek, G, Vaughan-Jones, R, Swietach, P, Kandilci, H
Format: Journal article
Sprache:English
Veröffentlicht: Wiley 2018