Recovery from hypoxia‐induced internalization of cardiac Na+/H + exchanger 1 requires an adequate intracellular store of antioxidants
The heart is highly active metabolically but relatively underperfused and, therefore, vulnerable to ischemia. In addition to acidosis, a key component of ischemia is hypoxia that can modulate gene expression and protein function as part of an adaptive or even maladaptive response. Here, using cardia...
Hauptverfasser: | , , , |
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Format: | Journal article |
Sprache: | English |
Veröffentlicht: |
Wiley
2018
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