Recovery from hypoxia‐induced internalization of cardiac Na+/H + exchanger 1 requires an adequate intracellular store of antioxidants

The heart is highly active metabolically but relatively underperfused and, therefore, vulnerable to ischemia. In addition to acidosis, a key component of ischemia is hypoxia that can modulate gene expression and protein function as part of an adaptive or even maladaptive response. Here, using cardia...

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Bibliographic Details
Main Authors: Şimşek, G, Vaughan-Jones, R, Swietach, P, Kandilci, H
Format: Journal article
Language:English
Published: Wiley 2018