Choice of Plk1 docking partners during mitosis and cytokinesis is controlled by the activation state of Cdk1.

Spatial and temporal coordination of polo-like kinase 1 (Plk1) activity is necessary for mitosis and cytokinesis, and this is achieved through binding to phosphorylated docking proteins with distinct subcellular localizations. Although cyclin-dependent kinase 1 (Cdk1) creates these phosphorylated do...

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Bibliographic Details
Main Authors: Neef, R, Gruneberg, U, Kopajtich, R, Li, X, Nigg, E, Sillje, H, Barr, F
Format: Journal article
Language:English
Published: 2007