Choice of Plk1 docking partners during mitosis and cytokinesis is controlled by the activation state of Cdk1.
Spatial and temporal coordination of polo-like kinase 1 (Plk1) activity is necessary for mitosis and cytokinesis, and this is achieved through binding to phosphorylated docking proteins with distinct subcellular localizations. Although cyclin-dependent kinase 1 (Cdk1) creates these phosphorylated do...
Main Authors: | Neef, R, Gruneberg, U, Kopajtich, R, Li, X, Nigg, E, Sillje, H, Barr, F |
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格式: | Journal article |
語言: | English |
出版: |
2007
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