Association of genetic variants of the chemokine receptor CCR5 and its ligands, RANTES and MCP-2, with outcome of HCV infection.

The effect of host genetic variation on the outcome of hepatitis C virus (HCV) infection and its treatment is poorly understood. The chemokine receptors CCR5, CCR2, and CCR3 and their ligands, RANTES, MCP-1, MCP-2, and MIP-1alpha, are involved in the immune responses and the selective recruitment of...

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Autori principali: Hellier, S, Frodsham, A, Hennig, B, Klenerman, P, Knapp, S, Ramaley, P, Satsangi, J, Wright, M, Zhang, L, Thomas, H, Thursz, M, Hill, A
Natura: Journal article
Lingua:English
Pubblicazione: 2003