New insights into the physiological role of carbonic anhydrase IX in tumour pH regulation.

New insights into the physiological role of carbonic anhydrase IX in tumour pH regulation.

अन्य संस्करण दिखाएं (1)

In this review, we discuss the role of the tumour-associated carbonic anhydrase isoform IX (CAIX) in the context of pH regulation. We summarise recent experimental findings on the effect of CAIX on cell growth and survival, and present a diffusion-reaction model to help in the assessment of CAIX fun...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों:	Swietach, P, Hulikova, A, Vaughan-Jones, R, Harris, A
स्वरूप:	Journal article
भाषा:	English
प्रकाशित:	2010

समान संसाधन

New insights into the physiological role of carbonic anhydrase IX in tumour pH regulation
द्वारा: Swietach, P, और अन्य
प्रकाशित: (2010)

Carbonic anhydrase IX is a pH-stat that sets an acidic tumour extracellular pH in vivo
द्वारा: Lee, S-H, और अन्य
प्रकाशित: (2018)

Carbonic anhydrase IX unifies spatial pH(i) regulation in large cell-clusters
द्वारा: Swietach, P, और अन्य
प्रकाशित: (2007)

Regulation of tumor pH and the role of carbonic anhydrase 9.
द्वारा: Swietach, P, और अन्य
प्रकाशित: (2007)

The chemistry, physiology and pathology of pH in cancer.
द्वारा: Swietach, P, और अन्य
प्रकाशित: (2014)

Intracellular carbonic anhydrase activity sensitizes cancer cell pH signaling to dynamic changes in CO2 partial pressure
द्वारा: Hulikova, A, और अन्य
प्रकाशित: (2014)

Antibody inhibiting enzymatic activity of tumour-associated carbonic anhydrase isoform IX
द्वारा: Murri-Plesko, M, और अन्य
प्रकाशित: (2011)

Antibody inhibiting enzymatic activity of tumour-associated carbonic anhydrase isoform IX.
द्वारा: Murri-Plesko, M, और अन्य
प्रकाशित: (2011)

Cancer-associated, hypoxia-inducible carbonic anhydrase IX facilitates CO2 diffusion.
द्वारा: Swietach, P, और अन्य
प्रकाशित: (2008)

Tumor-associated carbonic anhydrase 9 spatially coordinates intracellular pH in three-dimensional multicellular growths.
द्वारा: Swietach, P, और अन्य
प्रकाशित: (2008)

Regulation of intracellular pH in cancer cell lines under normoxia and hypoxia.
द्वारा: Hulikova, A, और अन्य
प्रकाशित: (2013)

Acid-extrusion from tissue: the interplay between membrane transporters and pH buffers.
द्वारा: Hulikova, A, और अन्य
प्रकाशित: (2012)

Importance of intracellular pH in determining the uptake and efficacy of the weakly basic chemotherapeutic drug, doxorubicin.
द्वारा: Swietach, P, और अन्य
प्रकाशित: (2012)

Molecular mechanisms of carbonic anhydrase IX-mediated pH regulation under hypoxia.
द्वारा: Pastorekova, S, और अन्य
प्रकाशित: (2008)

Dual role of CO2/HCO3(-) buffer in the regulation of intracellular pH of three-dimensional tumor growths.
द्वारा: Hulikova, A, और अन्य
प्रकाशित: (2011)

The role of carbonic anhydrase 9 in regulating extracellular and intracellular ph in three-dimensional tumor cell growths.
द्वारा: Swietach, P, और अन्य
प्रकाशित: (2009)

Spatial regulation of intracellular pH in multicellular strands of neonatal rat cardiomyocytes.
द्वारा: Swietach, P, और अन्य
प्रकाशित: (2010)

Common inhibitors of membrane H+-transport also inhibit carbonic anhydrase
द्वारा: Villafuerte, F, और अन्य
प्रकाशित: (2007)

Carbonic anhydrase IX, a hypoxia-induced catalytic component of the pH regulating machinery in tumors
द्वारा: Olga eSedlakova, और अन्य
प्रकाशित: (2014-01-01)

Extramitochondrial domain rich in carbonic anhydrase activity improves myocardial energetics.
द्वारा: Schroeder, M, और अन्य
प्रकाशित: (2013)

The role of soil pH on soil carbonic anhydrase activity
द्वारा: J. Sauze, और अन्य
प्रकाशित: (2018-01-01)

An Extra-Mitochondrial Domain Rich in Carbonic Anhydrase Activity Improves Myocardial Energetics
द्वारा: Schroeder, M, और अन्य
प्रकाशित: (2013)

Carbonic anhydrase IX promotes tumor growth and necrosis in vivo and inhibition enhances anti-VEGF therapy.
द्वारा: McIntyre, A, और अन्य
प्रकाशित: (2012)

Detection of intravascular hemolysis in newborns using urinary carbonic anhydrase I immunoreactivity
द्वारा: Kramer, H, और अन्य
प्रकाशित: (2020)

Carbonic Anhydrases: Role in pH Control and Cancer
द्वारा: Mam Y. Mboge, और अन्य
प्रकाशित: (2018-02-01)

Plasmatic exosomes from prostate cancer patients show increased carbonic anhydrase IX expression and activity and low pH
द्वारा: Mariantonia Logozzi, और अन्य
प्रकाशित: (2020-01-01)

Intracellular pH regulation in heart.
द्वारा: Vaughan-Jones, R, और अन्य
प्रकाशित: (2009)

Spatial regulation of intracellular pH in the ventricular myocyte.
द्वारा: Swietach, P, और अन्य
प्रकाशित: (2005)

The inhibitory effect of boric acid on hypoxia-regulated tumour-associated carbonic anhydrase IX
द्वारा: Zainab Saad Yusuf, और अन्य
प्रकाशित: (2022-12-01)

Differentiation impairs low pH-induced Ca2+ signaling and ERK phosphorylation in granule precursor tumour cells.
द्वारा: Huang, W, और अन्य
प्रकाशित: (2009)

Targeting Carbonic Anhydrase IX Activity and Expression
द्वारा: Brian P. Mahon, और अन्य
प्रकाशित: (2015-01-01)

Microsecond Simulation of the Proteoglycan-like Region of Carbonic Anhydrase IX and Design of Chemical Inhibitors Targeting pH Homeostasis in Cancer Cells
द्वारा: Arun John, और अन्य
प्रकाशित: (2020-02-01)

Gating of cardiac gap junctional channels at acid and alkaline pH
द्वारा: Swietach, P, और अन्य
प्रकाशित: (2005)

Spatial aspects of intracellular pH regulation in heart muscle.
द्वारा: Vaughan-Jones, R, और अन्य
प्रकाशित: (2006)

CrossTalk opposing view: Physiological CO2 exchange does not normally depend on membrane channels
द्वारा: Hulikova, A, और अन्य
प्रकाशित: (2015)

2H-chromene and 7H-furo-chromene derivatives selectively inhibit tumour associated human carbonic anhydrase IX and XII isoforms
द्वारा: Lisa Sequeira, और अन्य
प्रकाशित: (2023-12-01)

The relationship between intracellular pH and proton mobility in rat and guinea-pig ventricular myocytes
द्वारा: Swietach, P, और अन्य
प्रकाशित: (2005)

Relationship between intracellular pH and proton mobility in rat and guinea-pig ventricular myocytes.
द्वारा: Swietach, P, और अन्य
प्रकाशित: (2005)

Antitumor efficacy of a monoclonal antibody that inhibits the activity of cancer-associated carbonic anhydrase XII.
द्वारा: Gondi, G, और अन्य
प्रकाशित: (2013)

Primary Duodenal Adenocarcinoma Expressing Carbonic Anhydrase IX
द्वारा: Kimitoshi Kubo, और अन्य
प्रकाशित: (2022-05-01)