Immune dysregulation in patients with PTEN hamartoma tumor syndrome: Analysis of FOXP3 regulatory T cells

<p><b>Background</b>: Patients with heterozygous germline mutations in <em>PTEN</em> (phosphatase and tensin homologue deleted on chromosome 10) develop autoimmunity and lymphoid hyperplasia. </p> <p><b>Objectives</b>: Since regulation of the pho...

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Main Authors: Chen, H, Handel, N, Ngeow, J, Muller, J, Huhn, M, Yang, H, Heindl, M, Berbers, R, Hegazy, A, Kionke, J, Yehia, L, Sack, U, Blaser, F, Rensing-Ehl, A, Reifenberger, J, Keith, J, Travis, S, Merkenschlager, A, Keiss, W, Wittekind, C, Walker, L, Ehl, S, Aretz, S, Dustin, M, Eng, C, Powrie, F, Uhlig, H
格式: Journal article
出版: Elsevier 2016