Concordant regulation of gene expression by hypoxia and 2-oxoglutarate-dependent dioxygenase inhibition: the role of HIF-1alpha, HIF-2alpha, and other pathways.

Studies of gene regulation by oxygen have revealed novel signal pathways that regulate the hypoxia-inducible factor (HIF) transcriptional system through post-translational hydroxylation of specific prolyl and asparaginyl residues in HIF-alpha subunits. These oxygen-sensitive modifications are cataly...

Ful tanımlama

Detaylı Bibliyografya
Asıl Yazarlar: Elvidge, G, Glenny, L, Appelhoff, R, Ratcliffe, P, Ragoussis, J, Gleadle, J
Materyal Türü: Journal article
Dil:English
Baskı/Yayın Bilgisi: 2006