Non-viral delivery of CRIPSR/Cas cargo to the retina using nanoparticles: current possibilities, challenges, and limitations

The discovery of the CRISPR/Cas system and its development into a powerful genome engineering tool have revolutionized the field of molecular biology and generated excitement for its potential to treat a wide range of human diseases. As a gene therapy target, the retina offers many advantages over o...

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Bibliographic Details
Main Authors: Salman, A, Kantor, A, McClements, ME, Marfany, G, Trigueros, S, MacLaren, RE
Format: Journal article
Language:English
Published: MDPI 2022