High seeding density induces local hypoxia and triggers a proinflammatory response in isolated human islets

Hypoxia is the main threat to morphological and functional integrity of isolated pancreatic islets. Lack of oxygen seems to be of particular importance for functionality of encapsulated islets. The present study was initiated as an experimental model for the environment experienced by human islets i...

Fuld beskrivelse

Bibliografiske detaljer
Main Authors: Brandhorst, D, Brandhorst, H, Mullooly, N, Acreman, S, Johnson, P
Format: Journal article
Sprog:English
Udgivet: SAGE Publications 2016