Definition of the prognostic role of MGMT promoter methylation value by pyrosequencing in newly diagnosed idh wild-type glioblastoma patients treated with radiochemotherapy: a large multicenter study

<strong>Background<br></strong> O6-methylguanine (O6-MeG)-DNA methyltransferase (MGMT) methylation status is a predictive factor for alkylating treatment efficacy in glioblastoma patients, but its prognostic role is still unclear. We performed a large, multicenter study to evaluate...

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Main Authors: Caccese, M, Simonelli, M, Villani, V, Rizzato, S, Ius, T, Pasqualetti, F, Russo, M, Rudà, R, Amoroso, R, Bellu, L, Bertorelle, R, Cavallin, F, Dipasquale, A, Carosi, M, Pizzolitto, S, Cesselli, D, Persico, P, Casini, B, Fassan, M, Zagonel, V, Lombardi, G
Format: Journal article
Language:English
Published: MDPI 2022