Comparison of human chromosome 6p25 with mouse chromosome 13 reveals a greatly expanded ov-serpin gene repertoire in the mouse.
Ov-serpins are intracellular proteinase inhibitors implicated in the regulation of tumor progression, inflammation, and cell death. The 13 human ov-serpin genes are clustered at 6p25 (3 genes) and 18q21 (10 genes), and share common structures. We show here that a 1-Mb region on mouse chromosome 13 c...
المؤلفون الرئيسيون: | Kaiserman, D, Knaggs, S, Scarff, K, Gillard, A, Mirza, G, Cadman, M, McKeone, R, Denny, P, Cooley, J, Benarafa, C, Remold-O'Donnell, E, Ragoussis, J, Bird, P |
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التنسيق: | Journal article |
اللغة: | English |
منشور في: |
2002
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مواد مشابهة
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MOUSE CHROMOSOME-16
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منشور في: (1993) -
A serpin gene cluster on human chromosome 6p25 contains PI6, PI9 and ELANH2 which have a common structure almost identical to the 18q21 ovalbumin serpin genes.
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Analysis of vertebrate genomes suggests a new model for clade B serpin evolution
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Sequence of the mouse Y chromosome
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منشور في: (2008) -
Construction of stable mouse artificial chromosome from native mouse chromosome 10 for generation of transchromosomic mice
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منشور في: (2021-10-01)