Strong male bias drives germline mutation in chimpanzees

Germline mutation determines rates of molecular evolution, genetic diversity, and fitness load. In humans, the average point mutation rate is 1.2 × 10−8 per base pair per generation, with every additional year of father’s age contributing two mutations across the genome and males contributing three...

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Bibliographic Details
Main Authors: Venn, O, Turner, I, de Groot, N, Bontrop, R, Mathieson, I, McVean, G
Format: Journal article
Language:English
Published: American Association for the Advancement of Science 2014