Strong male bias drives germline mutation in chimpanzees
Germline mutation determines rates of molecular evolution, genetic diversity, and fitness load. In humans, the average point mutation rate is 1.2 × 10−8 per base pair per generation, with every additional year of father’s age contributing two mutations across the genome and males contributing three...
Main Authors: | Venn, O, Turner, I, de Groot, N, Bontrop, R, Mathieson, I, McVean, G |
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Format: | Journal article |
Language: | English |
Published: |
American Association for the Advancement of Science
2014
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