Single-molecule imaging of cholesterol-dependent cytolysin assembly

<p>Cholesterol-dependent cytolysins (CDCs) are amongst the primary virulence factors for several important pathogens. Their typical function is to lyse cells by forming large pores in target membranes, often up to 40 nm in diameter and comprised of around 30-50 subunits. Pores assemble from d...

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Autor principal: Senior, M
Format: Thesis
Publicat: 2015

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