Structural role of conserved Asn179 in the short-chain dehydrogenase/reductase scaffold.

Short-chain dehydrogenases/reductases (SDR) constitute a large family of enzymes found in all forms of life. Despite a low level of sequence identity, the three-dimensional structures determined display a nearly superimposable alpha/beta folding pattern. We identified a conserved asparagine residue...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Filling, C, Nordling, E, Benach, J, Berndt, K, Ladenstein, R, Jörnvall, H, Oppermann, U
Format: Journal article
Sprache:English
Veröffentlicht: 2001