Nuclear distribution and chromatin association of DNA polymerase α-primase is affected by TEV protease cleavage of Cdc23 (Mcm10) in fission yeast
Background: Cdc23/Mcm10 is required for the initiation and elongation steps of DNA replication but its biochemical function is unclear. Here, we probe its function using a novel approach in fission yeast, involving Cdc23 cleavage by the TEV protease. Results: Insertion of a TEV protease cleavage sit...
| Autors principals: | , , , , |
|---|---|
| Format: | Journal article |
| Idioma: | English |
| Publicat: |
Biomed Central Ltd.
2005
|
| Matèries: |