Elevated homocysteine is associated with increased rates of epigenetic aging in a population with mild cognitive impairment

Elevated homocysteine is associated with increased rates of epigenetic aging in a population with mild cognitive impairment

Elevated plasma total homocysteine (tHcy) is associated with the development of Alzheimer's disease and other forms of dementia. In this study, we report the relationship between tHcy and epigenetic age in older adults with mild cognitive impairment from the VITACOG study. Epigenetic age and ra...

Szczegółowa specyfikacja

Opis bibliograficzny
Główni autorzy:	Holmes, HE, Valentin, RE, Jernerén, F, de Jager Loots, CA, Refsum, H, Smith, AD, Guarente, L, Dellinger, RW, Sampson, D, Alzheimer's Disease Neuroimaging Initiative
Format:	Journal article
Język:	English
Wydane:	Wiley Open Access 2024

Podobne zapisy

Early diagnosis of Alzheimer’s disease and mild cognitive impairment using MRI analysis and machine learning algorithms
od: Helia Givian, i wsp.
Wydane: (2024-12-01)

NeuropsychBrainAge: A biomarker for conversion from mild cognitive impairment to Alzheimer's disease
od: Jorge Garcia Condado, i wsp.
Wydane: (2023-10-01)

Omega-3 Fatty Acid Status Enhances the Prevention of Cognitive Decline by B Vitamins in Mild Cognitive Impairment
od: Oulhaj, A, i wsp.
Wydane: (2016)

Item-Level Scores on the Boston Naming Test as an Independent Predictor of Perirhinal Volume in Individuals with Mild Cognitive Impairment
od: Matteo De Marco, i wsp.
Wydane: (2023-05-01)

Associations between Neuropsychiatric Symptoms and Alzheimer’s Disease Biomarkers in People with Mild Cognitive Impairment
od: Giulia Arenare, i wsp.
Wydane: (2023-08-01)

Choroid plexus volumes and auditory verbal learning scores are associated with conversion from mild cognitive impairment to Alzheimer's disease
od: Michael J. Pearson, i wsp.
Wydane: (2024-07-01)

Serotonin enhances neurogenesis biomarkers, hippocampal volumes, and cognitive functions in Alzheimer’s disease
od: Ali Azargoonjahromi, i wsp.
Wydane: (2024-12-01)

Sleep and nighttime behavior disorders in older adults: associations with hypercholesterolemia and hypertriglyceridemia at baseline, and a predictive analysis of incident cases at 12 months follow-up
od: Asma Hallab, i wsp.
Wydane: (2024-09-01)

Cognitive and clinical outcomes of homocysteine-lowering B-vitamin treatment in mild cognitive impairment: a randomized controlled trial.
od: de Jager, C, i wsp.
Wydane: (2012)

Cognitive and clinical outcomes of homocysteine-lowering B-vitamin treatment in mild cognitive impairment: A randomized controlled trial
od: De Jager, C, i wsp.
Wydane: (2012)

Alteration in temporal-cerebellar effective connectivity can effectively distinguish stable and progressive mild cognitive impairment
od: Chen Xue, i wsp.
Wydane: (2024-08-01)

Episodic memory network characteristics in patients with amnestic mild cognitive impairment accompanied by executive function impairment
od: Chao Wang, i wsp.
Wydane: (2024-06-01)

Detection of Alzheimer’s Disease Using Hybrid Meta-ROI of MRI Structural Images
od: Xiaoming Zheng, i wsp.
Wydane: (2024-10-01)

Use of Deep-Learning Genomics to Discriminate Healthy Individuals from Those with Alzheimer’s Disease or Mild Cognitive Impairment
od: Lanlan Li, i wsp.
Wydane: (2021-01-01)

Predicting the Conversion from Mild Cognitive Impairment to Alzheimer’s Disease Using an Explainable AI Approach
od: Gerasimos Grammenos, i wsp.
Wydane: (2024-04-01)

Definition and analysis of gray matter atrophy subtypes in mild cognitive impairment based on data-driven methods
od: Baiwen Zhang, i wsp.
Wydane: (2024-06-01)

Sex-dependent association of serum uric acid levels with amyloid accumulation among amyloid-positive older adults.
od: Guanan Zhao, i wsp.
Wydane: (2024-01-01)

Explainability of three-dimensional convolutional neural networks for functional magnetic resonance imaging of Alzheimer's disease classification based on gradient-weighted class activation mapping.
od: Boyue Song, i wsp.
Wydane: (2024-01-01)

Imputation-Based Variable Selection Method for Block-Wise Missing Data When Integrating Multiple Longitudinal Studies
od: Zhongzhe Ouyang, i wsp.
Wydane: (2024-03-01)

Identification of Disease-Related Genes That Are Common between Alzheimer’s and Cardiovascular Disease Using Blood Genome-Wide Transcriptome Analysis
od: Taesic Lee, i wsp.
Wydane: (2021-10-01)

A Novel Coupling Model of Physiological Degradation and Emotional State for Prediction of Alzheimer’s Disease Progression
od: Jiawei Yang, i wsp.
Wydane: (2022-08-01)

Elevated homocysteine and N-methyl-d-aspartate-receptor antibodies as a cause of behavioural and cognitive decline in 22q11.2 deletion syndrome.
od: Jones, S, i wsp.
Wydane: (2017)

Two for tau: automated model discovery reveals two-stage tau aggregation dynamics in Alzheimer’s disease
od: Stockman, CA, i wsp.
Wydane: (2024)

Explainability of random survival forests in predicting conversion risk from mild cognitive impairment to Alzheimer’s disease
od: Alessia Sarica, i wsp.
Wydane: (2023-11-01)

Longitudinal accelerated brain age in mild cognitive impairment and Alzheimer’s disease
od: Maria Ly, i wsp.
Wydane: (2024-10-01)

Associations of Serum Isoleucine with Mild Cognitive Impairment and Alzheimer’s Disease
od: Xiao-jun Jing, i wsp.
Wydane: (2024-09-01)

Sex Differences in Conversion Risk from Mild Cognitive Impairment to Alzheimer’s Disease: An Explainable Machine Learning Study with Random Survival Forests and SHAP
od: Alessia Sarica, i wsp.
Wydane: (2024-02-01)

Homocysteine, B vitamins, and cognitive impairment
od: Smith, A, i wsp.
Wydane: (2016)

Homocysteine, B vitamins, and cardiovascular disease
od: Refsum, H, i wsp.
Wydane: (2006)

Homocysteine, B vitamins, and cardiovascular disease.
od: Refsum, H, i wsp.
Wydane: (2006)

Random forest prediction of Alzheimer's disease using pairwise selection from time series data
od: Moore, P, i wsp.
Wydane: (2019)

Classification of Alzheimer’s and MCI Patients from Semantically Parcelled PET Images: A Comparison between AV45 and FDG-PET
od: Seyed Hossein Nozadi, i wsp.
Wydane: (2018-01-01)

Brain age gap estimation using attention-based ResNet method for Alzheimer’s disease detection
od: Atefe Aghaei, i wsp.
Wydane: (2024-06-01)

Homocysteine-lowering by B vitamins slows the rate of accelerated brain atrophy in mild cognitive impairment: a randomized controlled trial
od: Smith, A, i wsp.
Wydane: (2010)

Homocysteine-lowering by B vitamins slows the rate of accelerated brain atrophy in mild cognitive impairment: a randomized controlled trial.
od: Smith, A, i wsp.
Wydane: (2010)

Homocysteine-lowering by B vitamins slows the rate of accelerated brain atrophy in mild cognitive impairment: a randomized controlled trial.
od: Smith, A, i wsp.
Wydane: (2010)

Multiple phenotype association tests based on sliced inverse regression
od: Wenyuan Sun, i wsp.
Wydane: (2024-04-01)

Learning semi-supervised enrichment of longitudinal imaging-genetic data for improved prediction of cognitive decline
od: Hoon Seo, i wsp.
Wydane: (2024-05-01)

Disrupted single-subject gray matter networks are associated with cognitive decline and cortical atrophy in Alzheimer’s disease
od: Yaqiong Xiao, i wsp.
Wydane: (2024-05-01)

Atrophy of hippocampal subfields relates to memory decline during the pathological progression of Alzheimer’s disease
od: Yaqiong Xiao, i wsp.
Wydane: (2023-12-01)