Using chemical genetics and ATP analogues to dissect protein kinase function
Protein kinases catalyze the transfer of the γ-phosphate of ATP to a protein substrate and thereby profoundly alter the properties of the phosphorylated protein. The identification of the substrates of protein kinases has proven to be a very difficult task because of the multitude of structurally re...
Auteurs principaux: | , , , |
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Format: | Journal article |
Langue: | English |
Publié: |
2007
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