Using chemical genetics and ATP analogues to dissect protein kinase function

Using chemical genetics and ATP analogues to dissect protein kinase function

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Protein kinases catalyze the transfer of the γ-phosphate of ATP to a protein substrate and thereby profoundly alter the properties of the phosphorylated protein. The identification of the substrates of protein kinases has proven to be a very difficult task because of the multitude of structurally re...

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Autors principals:	Elphick, L, Lee, SE, Gouverneur, V, Mann, D
Format:	Journal article
Idioma:	English
Publicat:	2007

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