Using chemical genetics and ATP analogues to dissect protein kinase function
Protein kinases catalyze the transfer of the γ-phosphate of ATP to a protein substrate and thereby profoundly alter the properties of the phosphorylated protein. The identification of the substrates of protein kinases has proven to be a very difficult task because of the multitude of structurally re...
Hlavní autoři: | Elphick, L, Lee, SE, Gouverneur, V, Mann, D |
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Médium: | Journal article |
Jazyk: | English |
Vydáno: |
2007
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