Concept, design and implementation of a cardiovascular gene-centric 50 k SNP array for large-scale genomic association studies.

A wealth of genetic associations for cardiovascular and metabolic phenotypes in humans has been accumulating over the last decade, in particular a large number of loci derived from recent genome wide association studies (GWAS). True complex disease-associated loci often exert modest effects, so thei...

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Main Authors: Keating, B, Tischfield, S, Murray, S, Bhangale, T, Price, T, Glessner, J, Galver, L, Barrett, J, Grant, S, Farlow, D, Chandrupatla, H, Hansen, M, Ajmal, S, Papanicolaou, G, Guo, Y, Li, M, Derohannessian, S, de Bakker, P, Bailey, S, Montpetit, A, Edmondson, A, Taylor, K, Gai, X, Wang, S, Fornage, M, Shaikh, T, Groop, L, Boehnke, M, Hall, A, Hattersley, A, Frackelton, E, Patterson, N, Chiang, C, Kim, C, Fabsitz, R, Ouwehand, W, Price, A, Munroe, P, Caulfield, M, Drake, T, Boerwinkle, E, Reich, D, Whitehead, A, Cappola, T, Samani, N, Lusis, A, Schadt, E, Wilson, J, Koenig, W, McCarthy, M, Kathiresan, S, Gabriel, S, Hakonarson, H, Anand, S, Reilly, M, Engert, J, Nickerson, D, Rader, D, Hirschhorn, J, Fitzgerald, G
Format: Journal article
Language:English
Published: 2008