Citrullination-acetylation interplay guides E2F-1 activity during the inflammatory response
Peptidyl arginine deiminase (PAD) 4 is a nuclear enzyme that converts arginine residues to citrulline. Although increasingly implicated in inflammatory disease and cancer, the mechanism of action of PAD4 and identity of reader domains specifically recognising citrulline modifications...
| Main Authors: | , , , , , , , , , , , , , , |
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| Format: | Journal article |
| Published: |
American Association for the Advancement of Science
2016
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