Citrullination-acetylation interplay guides E2F-1 activity during the inflammatory response

Peptidyl arginine deiminase (PAD) 4 is a nuclear enzyme that converts arginine residues to citrulline. Although increasingly implicated in inflammatory disease and cancer, the mechanism of action of PAD4 and identity of reader domains specifically recognising citrulline modifications...

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Hlavní autoři:	la Thangue, N, Ghari, F, Munro, S, Quirke, A, Kawalkowska, A, Picaud, S, McGouran, J, Williams, R, Kessler, B, Fillipakopoulos, P, Knapp, S, Venables, P, Subramian, V, Muth, A, Thompson, P
Médium:	Journal article
Vydáno:	American Association for the Advancement of Science 2016

Citrullination-acetylation interplay guides E2F-1 activity during the inflammatory response

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