Synthesis and evaluation of (bis)benzyltetrahydroisoquinoline alkaloids as antiparasitic agents
Visceral leishmaniasis and Chagas disease are neglected tropical diseases (NTDs) that severely impact the developing world. With current therapies suffering from poor efficacy and safety profiles as well as emerging resistance, new drug leads are direly needed. In this work, 26 alkaloids (9 natural...
Main Authors: | , , , , , , |
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Format: | Journal article |
Language: | English |
Published: |
American Chemical Society
2024
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