Plasmodium falciparum: a paradigm for alternative folate biosynthesis in diverse microorganisms?
Folates have a key role in metabolism, and the folate-dependent generation of DNA precursors in the form of deoxythymidine 5'-phosphate is particularly important for the replication of malaria parasites. Although Plasmodium falciparum can synthesize folate derivatives de novo, a long-standing m...
Main Authors: | , , , , , |
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Format: | Journal article |
Language: | English |
Published: |
2008
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