Chromosomal translocation master genes, mouse models and experimental therapeutics.

Molecular biologists have elucidated general principles about chromosomal translocations by cloning oncogenes or fusion genes at chromosomal translocation junctions. These genes invariably encode intracellular proteins and in acute cancers, often involve transcription and developmental regulators, w...

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Bibliographic Details
Main Author: Rabbitts, T
Format: Journal article
Language:English
Published: 2001