The notch signalling regulator fringe acts in the Golgi apparatus and requires the glycosyltransferase signature motif DXD.

BACKGROUND: Signalling via the Notch receptor is a key regulator of many developmental processes. The differential responsiveness of Notch-expressing cells to the ligands Delta and Serrate is controlled by Fringe, itself essential for normal patterning in Drosophila and vertebrates. The mechanism of...

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Detaylı Bibliyografya
Asıl Yazarlar: Munro, S, Freeman, M
Materyal Türü: Journal article
Dil:English
Baskı/Yayın Bilgisi: 2000

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