Investigating the role of ADAM10 and ADAM17 in cetuximab resistance in head and neck squamous cell carcinoma
<p>Epithermal Growth Factor Receptor (EGFR) is overexpressed in up to 90% of head and neck squamous cell carcinoma (HNSCC). Cetuximab is the first and the only anti-EGFR monoclonal antibody which received approval from FDA for the treatment of HNSCC. However, most patients either do not respon...
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Format: | Thesis |
Language: | English |
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2014
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