The cytoophidium and its kind: Filamentation and compartmentation of metabolic enzymes

The cytoophidium and its kind: Filamentation and compartmentation of metabolic enzymes

Compartmentation is essential for the localization of biological processes within a cell. In 2010, three groups independently reported that cytidine triphosphate synthase (CTPS), a metabolic enzyme for de novo synthesis of the nucleotide CTP, is compartmentalized in cytoophidia (Greek for "cell...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awdur:	Liu, J
Fformat:	Journal article
Iaith:	English
Cyhoeddwyd:	Annual Reviews 2016

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gan: Chang, C, et al.
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gan: Huang, Y, et al.
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gan: Chen, K, et al.
Cyhoeddwyd: (2011)

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IMP/GTP balance modulates cytoophidium assembly and IMPDH activity
gan: Keppeke, G, et al.
Cyhoeddwyd: (2018)

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Cyhoeddwyd: (2019)

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gan: Azzam, G, et al.
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gan: Aughey, G, et al.
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Compartmentalization of the Edinburgh Human Metabolic Network
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Compartmentation of redox metabolism in malaria parasites.
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The self-inhibitory nature of metabolic networks and its alleviation through compartmentalization
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Dynamics of the compartmentalized Streptomyces chromosome during metabolic differentiation
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Filament formation by metabolic enzymes is a specific adaptation to an advanced state of cellular starvation
gan: Ivana Petrovska, et al.
Cyhoeddwyd: (2014-04-01)

Compartmental analysis of the dynamics of beta-carotene metabolism in an adult volunteer.
gan: J.A. Novotny, et al.
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gan: Lewis, Caroline A., et al.
Cyhoeddwyd: (2016)

Organelle interactions compartmentalize hepatic fatty acid trafficking and metabolism
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gan: L A Zech, et al.
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Physiological compartmental analysis of α-linolenic acid metabolism in adult humans
gan: Robert J. Pawlosky, et al.
Cyhoeddwyd: (2001-08-01)

Isomeric lipid signatures reveal compartmentalized fatty acid metabolism in cancer
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