S100a4-Cre-mediated deletion of Patched1 causes hypogonadotropic hypogonadism: role of pituitary hematopoietic cells in endocrine regulation

Hormones produced by the anterior pituitary gland regulate an array of important physiological functions, but pituitary hormone disorders are not fully understood. Herein we report that genetically-engineered mice with deletion of the hedgehog signaling receptor Patched1 by S100a4 promoter-driven Cr...

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Bibliographic Details
Main Authors: Ren, YA, Monkkonen, T, Lewis, MT, Bernard, DJ, Christian, HC, Jorgez, CJ, Moore, JA, Landua, JD, Chin, HM, Chen, W, Singh, S, Kim, IS, Zhang, XF, Xia, Y, Phillips, KJ, MacKay, H, Waterland, RA, Ljungberg, MC, Saha, PK, Hartig, SM, Coll, TF, Richards, JS
Format: Journal article
Language:English
Published: American Society for Clinical Investigation 2019