Polyfunctional cytomegalovirus-specific CD4+ and pp65 CD8+ T cells protect against high-level replication after liver transplantation.

To determine whether polyfunctional CD4+ T-cell responses coupled with CD8+ T-cell responses against human cytomegalovirus (HCMV) are key to the control of HCMV replication we prospectively analyzed 29 liver transplant recipients for CD4+ T-cell responses against soluble HCMV antigen, pp65 and IE1 p...

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Bibliographic Details
Main Authors: Nebbia, G, Mattes, F, Smith, C, Hainsworth, E, Kopycinski, J, Burroughs, A, Griffiths, P, Klenerman, P, Emery, VC
Format: Journal article
Language:English
Published: 2008