Myelin oligodendrocyte glycoprotein-35-55 peptide induces severe chronic experimental autoimmune encephalomyelitis in HLA-DR2-transgenic mice.

The use of HLA class II-transgenic (Tg) mice has facilitated identification of antigenic T cell epitopes that may contribute to inflammation in T cell-mediated diseases such as rheumatoid arthritis and multiple sclerosis (MS). In this study, we compared the encephalitogenic activity of three DR2-res...

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Bibliographic Details
Main Authors: Rich, C, Link, J, Zamora, A, Jacobsen, H, Meza-Romero, R, Offner, H, Jones, R, Burrows, G, Fugger, L, Vandenbark, A
Format: Journal article
Language:English
Published: 2004