Detection of antigen-specific cytotoxic T lymphocytes: significance for investigative dermatology.
Novel recombinant tetrameric complexes of HLA class I molecules allow the direct visualization of antigen-specific CD8+ T cells using flow cytometry. By facilitating the quantification, isolation and phenotypic analysis of CD8+ T cells, the use of HLA tetramers has extended our understanding of the...
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| Format: | Journal article |
| Language: | English |
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2000
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