Dynamics and correlates of CD8 T-Cell counts in Africans with primary human immunodeficiency virus type 1 infection

In individuals with HIV-1 infection, depletion of CD4(+) T cells is often accompanied by a malfunction of CD8(+) T cells that are persistently activated and/or exhausted. While the dynamics and correlates of CD4 counts have been well documented, the same does not apply to CD8 counts. Here, we examin...

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Bibliographic Details
Main Authors: Prentice, H, Lu, H, Price, M, Kamali, A, Karita, E, Lakhi, S, Sanders, E, Anzala, O, Allen, S, Goepfert, P, Hunter, E, Gilmour, J, Tang, J
Format: Journal article
Language:English
Published: American Society for Microbiology 2016