Synergistic inhibition of HIV-1 infection by combinations of soluble polyanions with other potential microbicides.

Several polyanionic compounds with potential for use as topically applied microbicides to prevent HIV-1 sexual transmission, such as PRO 2000, are currently in phase III clinical efficacy trials. Microbicidal formulations may well comprise combinations of inhibitors to increase potency, reduce dose...

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Detalhes bibliográficos
Principais autores: Gantlett, K, Weber, J, Sattentau, Q
Formato: Journal article
Idioma:English
Publicado em: 2007