Increase in cholesterol predicts survival advantage in renal cell carcinoma patients treated with temsirolimus.

PURPOSE: Temsirolimus is an effective treatment for renal cell carcinoma. It is associated with increases in serum cholesterol, triglyceride, and glucose. We investigated whether changes of these biomarkers could predict its efficacy. EXPERIMENTAL DESIGN: We examined serial measurements of choleste...

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Bibliographic Details
Main Authors: Lee, C, Marschner, I, Simes, R, Voysey, M, Egleston, B, Hudes, G, de Souza, P
Format: Journal article
Language:English
Published: 2012