Evaluation of multiplex flow cytometric opsonophagocytic assays for determination of functional anticapsular antibodies to Streptococcus pneumoniae.

The determination of functional antipneumococcal capsular polysaccharide antibodies by sequential testing of pre- and postvaccination serum samples one serotype at a time is sample-intensive and time-consuming and has a relatively low throughput. We tested several opsonophagocytic assay (OPA) format...

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Bibliographic Details
Main Authors: Martinez, J, Clutterbuck, E, Li, H, Romero-Steiner, S, Carlone, G
Format: Journal article
Language:English
Published: 2006