BRCA2 coordinates the activities of cell-cycle kinases to promote genome stability.

Numerous human genome instability syndromes, including cancer, are closely associated with events arising from malfunction of the essential recombinase Rad51. However, little is known about how Rad51 is dynamically regulated in human cells. Here, we show that the breast cancer susceptibility protein...

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Bibliographic Details
Main Authors: Yata, K, Bleuyard, J, Nakato, R, Ralf, C, Katou, Y, Schwab, R, Niedzwiedz, W, Shirahige, K, Esashi, F
Format: Journal article
Language:English
Published: 2014