D-amino acid oxidase, D-serine and the dopamine system: their interactions and implications for schizophrenia

<p>D-amino acid oxidase (DAO) is a flavin-dependent enzyme that is expressed in the mammalian brain. It is the metabolising enzyme of several D-amino acids, including D serine, which is an endogenous agonist at the glycine co-agonist site of the glutamatergic NMDA receptor. As such, regulation...

Descrición completa

Detalles Bibliográficos
Autor Principal: Betts, J
Outros autores: Harrison, P
Formato: Thesis
Idioma:English
Publicado: 2012
Subjects: