D-amino acid oxidase, D-serine and the dopamine system: their interactions and implications for schizophrenia

<p>D-amino acid oxidase (DAO) is a flavin-dependent enzyme that is expressed in the mammalian brain. It is the metabolising enzyme of several D-amino acids, including D serine, which is an endogenous agonist at the glycine co-agonist site of the glutamatergic NMDA receptor. As such, regulation...

Description complète

Détails bibliographiques
Auteur principal: Betts, J
Autres auteurs: Harrison, P
Format: Thèse
Langue:English
Publié: 2012
Sujets: