Use of schizophrenia and bipolar disorder polygenic risk scores to identify psychotic disorders

Use of schizophrenia and bipolar disorder polygenic risk scores to identify psychotic disorders

<strong>Background</strong> There is increasing evidence for shared genetic susceptibility between schizophrenia and bipolar disorder. Although genetic variants only convey subtle increases in risk individually, their combination into a polygenic risk score constitutes a strong disease p...

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Main Authors: Calafato, MS, Thygesen, JH, Ranlund, S, Zartaloudi, E, Cahn, W, Crespo-Facorro, B, Díez-Revuelta, Á, Di Forti, M, Genetic Risk And Outcome Of Psychosis (Group) Consortium, Hall, M-H, Iyegbe, C, Jablensky, A, Kahn, R, Kalaydjieva, L, Kravariti, E, Lin, K, McDonald, C, McIntosh, AM, McQuillin, A, Psychosis Endophenotypes International Consortium (PEIC), Picchioni, M, Rujescu, D, Shaikh, M, Toulopoulou, T, Os, JV, Vassos, E, Walshe, M, Powell, J, Lewis, CM, Murray, RM, Bramon, E, Wellcome Trust Case Control Consortium 2 (WTCCC2)
Format: Journal article
Language:English
Published: Cambridge University Press 2018

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