Ligand dimensions are important in controlling NK-cell responses.

Size-dependent protein segregation at the cell-cell contact interface has been suggested to be critical for regulation of lymphocyte function. We investigated the role of ligand dimensions in regulation of mouse NK-cell activation and inhibition. Elongated forms of H60a, a mouse NKG2D ligand, were g...

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Bibliographic Details
Main Authors: Brzostek, J, Chai, J, Gebhardt, F, Busch, D, Zhao, R, Van Der Merwe, P, Gould, K
Format: Journal article
Language:English
Published: 2010