Role for lysosomal phospholipase A2 in iNKT cell-mediated CD1d recognition

Invariant natural killer T (iNKT) cells recognize self lipid antigens presented by CD1d molecules. The nature of the self-antigens involved in the development and maturation of iNKT cells is poorly defined. Lysophospholipids are self-antigens presented by CD1d that are generated through the action o...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Paduraru, C, Bezbradica, J, Kunte, A, Kelly, R, Shayman, J, Veerapen, N, Cox, L, Besra, G, Cresswell, P
Format: Journal article
Sprache:English
Veröffentlicht: National Academy of Sciences 2014